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Article

Prediction of response to interferon therapy in multiple sclerosis.

Acta neurologica Scandinavica - 1 Oct 2014

Sellebjerg F, Søndergaard H B, Koch-Henriksen N, Sørensen P S, Oturai A B

Abstract excerpt

OBJECTIVE: Single nucleotide polymorphisms (SNPs) in the genes encoding interferon response factor (IRF)-5, IRF-8 and glypican-5 (GPC5) have been associated with disease activity in multiple sclerosis (MS) patients treated with interferon (IFN)-β. We analysed whether SNPs in the IRF5, IRF8 and GPC5 genes are associated with clinical disease activity in MS patients beginning de novo treatment with IFN-β. METHODS:...

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Share to Disease Progression
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glypicans

Share to Interferon-beta

Share to Interferon Regulatory Factors

Share to Multiple Sclerosis, Relapsing-Remitting

Share to Polymorphism, Single Nucleotide

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Source

Identifiers

PMID: 24943672
DOI: 10.1111/ane.12269

Genes

GPC5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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