Article
Pharmacogenomics of interferon-β in multiple sclerosis: what has been accomplished and how can we ensure future progress?
Cytokine & growth factor reviews - 1 Apr 2015
Carlson Rebecca J, Doucette J Ronald, Knox Katherine, Nazarali Adil J
Abstract excerpt
Multiple sclerosis (MS) is a progressive disorder of the central nervous system, often resulting in significant disability in early adulthood. The field of pharmacogenomics holds promise in distinguishing responders from non-responders to drug treatment. Most studies on genetic polymorphisms in MS have addressed treatment with interferon-β, yet few findings have been replicated. This review outlines the barriers...
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