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Article

Coexistence of MSI with KRAS mutation is associated with worse prognosis in colorectal cancer.

Medicine - 1 Dec 2016

Hu Jing, Yan Wen-Yue, Xie Li, Cheng Lei, Yang Mi, Li Li, Shi Jiong, Liu Bao-Rui, Qian Xiao-Ping

Abstract excerpt

Kristen rat sarcoma viral oncogene homolog (KRAS) and microsatellite instability (MSI) are prognostic markers of colorectal cancer (CRC). However, the clinical value is still not fully understood, when giving the consideration to both the molecular makers. Five hundred fifty-one patients with CRC were retrospectively assessed by determining their clinicopathological features. KRAS mutations were detected by...

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Source

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Identifiers

PMID: 27977612
DOI: 10.1097/MD.0000000000005649
PMCID: PMC5268058

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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