Article
Reduced atherosclerotic burden in subjects with genetically determined low oxidative stress.
Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 2013
Violi Francesco, Pignatelli Pasquale, Pignata Claudio, Plebani Alessandro, Rossi Paolo, Sanguigni Valerio, Carnevale Roberto, Soresina Annarosa, Finocchi Andrea, Cirillo Emilia, Catasca Elisa, Angelico Francesco, Loffredo Lorenzo
Abstract excerpt
OBJECTIVE: NADPH oxidase, one of the most important enzymes producing reactive oxidant species, is suggested to play a role in experimental atherosclerosis, but its role in human atherosclerosis is still unclear. We hypothesized that a reduced activity of NADPH oxidase might be linked to a reduced atherosclerotic burden. METHODS AND RESULTS: Thirty-one women carriers of hereditary deficiency of NOX2, the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
