Article
Interaction between maternal and offspring diet to impair vascular function and oxidative balance in high fat fed male mice.
PloS one - 1 Jan 2012
Torrens Christopher, Ethirajan Priya, Bruce Kimberley D, Cagampang Felino R A, Siow Richard C M, Hanson Mark A, Byrne Christopher D, Mann Giovanni E, Clough Geraldine F
Abstract excerpt
AIMS: To determine the impact of maternal and post-weaning consumption of a high fat diet on endothelium-dependent vasorelaxation and redox regulation in adult male mouse offspring. METHODS: Female C57BL6J mice were fed an obesogenic high fat diet (HF, 45% kcal fat) or standard chow (C, 21% kcal fat) pre-conception and throughout pregnancy and lactation. Post-weaning, male offspring were continued on the same...
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