Article
Correlation of lysosome-associated protein transmembrane-4β gene overexpression with the malignant phenotypes of hepatocellular carcinoma.
Pathology, research and practice - 1 Dec 2017
Su Hongying, Xu Tao, Huang Xiongfei, Zang Shengbing, Wang Bin, Huang Yang, Liu Jingfeng, Huang Aimin
Abstract excerpt
Hepatocellular carcinoma (HCC) is one of the most common and rapidly fatal malignancies, for which hepatitis B virus (HBV) chronic infection constitutes a major risk factor. The lysosome-associated protein transmembrane-4 β gene (LAPTM4B) is a recently identified gene that was found to be overexpressed in several types of cancer. However, the role of LAPTM4B in HCC tumorigenesis and progression has not been...
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