Article
Relationship between LAPTM4B gene polymorphism and susceptibility of colorectal and esophageal cancers.
Annals of oncology : official journal of the European Society for Medical Oncology - 1 Mar 2008
Cheng X-J, Xu W, Zhang Q-Y, Zhou R-L
Abstract excerpt
BACKGROUND: Lysosome-associated protein transmembrane 4 beta (LAPTM4B) is a novel gene of the mammalian LAPTM family and has been shown to be overexpressed in human hepatocellular carcinoma. There are two alleles, LAPTM4B*1 and *2, which share the same sequence except for one segment of 19 bp in the 5' untranslated region of the exon 1. LAPTM4B*1 has one 19 bp segment, while LAPTM4B*2 has two tight tandem...
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