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Correlation of LAPTM4B polymorphisms with hepatocellular carcinoma in Chinese patients.

Medical oncology (Northwood, London, England) - 1 Dec 2012

Zhai Guojun, Yang Hua, Ji Xiaoxu, Xiong Fuxia, Su Jing, McNutt Michael A, Li Xuan

Abstract excerpt

Hepatocellular carcinoma (HCC) is the leading cause of cancer mortality in many countries. Evaluation of new susceptibility risk factors is therefore warranted in order to explore means to improve the survival rate. Here, we report on a novel HCC-related gene known as lysosomal protein transmembrane 4 beta (LAPTM4B) that has two alleles designated LAPTM4B*1 and LAPTM4B*2. Allele *1 differs from allele *2 in that...

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PMID: 22207410
DOI: 10.1007/s12032-011-0139-y

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