Article
Relationship between LAPTM4B gene polymorphism and susceptibility of primary liver cancer.
Annals of oncology : official journal of the European Society for Medical Oncology - 1 Jul 2012
Wang S, Zhang Q-Y, Zhou R-L
Abstract excerpt
BACKGROUND: Lysosome associated protein transmembrane 4 beta (LAPTM4B) was identified first as a novel gene overexpressed in human hepatocellular carcinoma. LAPTM4B*1 and LAPTM4B*2 are two alleles of the gene; they are differentiated at 5'UTR in the first exon. Allele *1 contains only one copy of a 19-bp sequence in the 5'UTR. However, allele *2 contains another identical 19-bp sequence following the first one...
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