Article
LAPTM4B: an oncogene in various solid tumors and its functions.
Oncogene - 15 Dec 2016
Meng Y, Wang L, Chen D, Chang Y, Zhang M, Xu J-J, Zhou R, Zhang Q-Y
Abstract excerpt
The oncogene Lysosome-associated protein transmembrane-4β (LAPTM4B) gene was identified, and the polymorphism region in the 5'-UTR of this gene was certified to be associated with tumor susceptibility. LAPTM4B-35 protein was found to be highly expressed in various solid tumors and could be a poor prognosis marker. The functions of LAPTM4B in solid tumors were also explored. It is suggested that LAPTM4B could...
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