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Evolutionary Conservation of the Components in the TOR Signaling Pathways

1 Nov 2017

Abstract excerpt

Target of rapamycin (TOR) is an evolutionarily conserved protein kinase that controls multiple cellular processes upon various intracellular and extracellular stimuli. Since its first discovery, extensive studies have been conducted both in yeast and animal species including humans. Those studies have revealed that TOR forms two structurally and physiologically distinct protein complexes; TOR complex 1 (TORC1) is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29104218
DOI: 10.3390/biom7040077

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