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Article

mTOR signalling: jack-of-all-trades

16 May 2018

Abstract excerpt

The mechanistic target of rapamycin (mTOR) is an evolutionarily conserved serine/threonine kinase that senses and integrates environmental information into cellular regulation and homeostasis. Accumulating evidence has suggested a master role of mTOR signalling in many fundamental aspects of cell biology and organismal development. mTOR deregulation is implicated in a broad range of pathological conditions,...

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Identifiers

PMID: 29768134
DOI: 10.1139/bcb-2018-0004

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