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Article

LOX-1/LOXIN: the yin/yang of atheroscleorosis.

Cardiovascular drugs and therapy - 1 Oct 2011

Mango Ruggiero, Predazzi Irene Marta, Romeo Francesco, Novelli Giuseppe

Abstract excerpt

Atherosclerosis is the first cause of death in industrialized countries. Together with traditional risk factors (male gender, hypercholesterolemia, hypertension, diabetes, smoking and age), non-traditional risk factors have also been described as predisposing to this disease. Among these, oxidize...

Read the complete abstract on PubMed

Topics

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Share to Atherosclerosis
Share to LOX gene
Share to Lipoproteins, LDL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

Share to Protein Isoforms

Share to Scavenger Receptors, Class E

Source

Identifiers

PMID: 21904818
DOI: 10.1007/s10557-011-6333-5

Genes

LOX
OLR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21904818-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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LOX-1/LOXIN: the yin/yang of atheroscleorosis.PMID 21904818Read ↗

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Structure and chromosomal assignment of the human lectin-like oxidized low-density-lipoprotein receptor-1 (LOX-1) geneSemantic proximity Read ↗

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The human rs1050286 polymorphism alters LOX-1 expression through modifying miR-24 binding.Semantic proximity Read ↗

The splice variant LOXIN inhibits LOX-1 receptor function through hetero-oligomerization.Semantic proximity Read ↗

In vivo and in vitro studies support that a new splicing isoform of OLR1 gene is protective against acute myocardial infarction.Semantic proximity Read ↗

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Genetic variation in lectin-like oxidized low-density lipoprotein receptor 1 (LOX1) gene and the risk of coronary artery disease.Semantic proximity Read ↗

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