Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lamin A/C cardiomyopathy: young onset, high penetrance, and frequent need for heart transplantation.

European heart journal - 7 Mar 2018

Hasselberg Nina Eide, Haland Trine Fink, Saberniak Jørg, Brekke Pål Haugar, Berge Knut Erik, Leren Trond Paul, Edvardsen Thor, Haugaa Kristina Hermann

Abstract excerpt

Aims: Lamin A/C (LMNA) mutations cause familial dilated cardiomyopathy (DCM) with frequent conduction blocks and arrhythmias. We explored the prevalence, cardiac penetrance, and expressivity of LMNA mutations among familial DCM in Norway. Furthermore, we explored the risk factors and the outcomes in LMNA patients. Methods and results: During 2003-15, genetic testing was performed in patients referred for familial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Cardiomyopathy, Dilated

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Follow-Up Studies

Share to Heart Transplantation

Share to Lamin Type A

Share to Mutation

Share to Prevalence

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 29095976
DOI: 10.1093/eurheartj/ehx596
PMCID: PMC5939624

Genes

LMNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lamin A/C cardiomyopathy: young onset, high penetrance, and frequent need for heart transplantation.PMID 29095976Read ↗

Risk factors for malignant ventricular arrhythmias in lamin a/c mutation carriers a European cohort study.Semantic proximity Read ↗

Gender-specific differences in major cardiac events and mortality in lamin A/C mutation carriers.Semantic proximity Read ↗

Lamin A/C cardiomyopathy presenting as high-grade atrioventricular (AV) block, atrial fibrillation, heart failure and ventricular tachycardia in a single-family cluster.Semantic proximity Read ↗

Lamin and the heart.Semantic proximity Read ↗

Long-Term Arrhythmic and Nonarrhythmic Outcomes of Lamin A/C Mutation Carriers.Semantic proximity Read ↗

External Validation of Risk Factors for Malignant Ventricular Arrhythmias in Lamin A/C Mutation CarriersSemantic proximity Read ↗

Gene-Based Risk Stratification for Cardiac Disorders in LMNA Mutation Carriers.Semantic proximity Read ↗

Clinical disease presentation and ECG characteristics of LMNA mutation carriersSemantic proximity Read ↗

Clinical Manifestations and Long-Term Mortality in Lamin A/C Mutation Carriers From a Japanese Multicenter Registry.Semantic proximity Read ↗

Can Circulating Cardiac Biomarkers Be Helpful in the Assessment of LMNA Mutation Carriers?Semantic proximity Read ↗

A novel mutation in lamin a/c causing familial dilated cardiomyopathy associated with sudden cardiac death.Semantic proximity Read ↗

Long-term outcome and risk stratification in dilated cardiolaminopathies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.