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Article

External Validation of Risk Factors for Malignant Ventricular Arrhythmias in Lamin A/C Mutation Carriers

9 Jan 2019

Abstract excerpt

Laminopathy is a relatively rare but increasingly recognized genetic disease (due to a mutation in LMNA gene encoding lamin A/C proteins) associated with a poor prognosis related to malignant ventricular arrhythmias (MVA) and progression to end-stage heart failure.1-3 International recommendations4 state that implantable cardioverter defibrillator (ICD) should be considered early in patients with a confirmed...

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PMID: 30623531
DOI: 10.1002/ejhf.1384

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