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Article

Genotype-based tacrolimus dosing guidelines: with or without CYP3A4*22?

Pharmacogenomics - 1 Nov 2017

Elens Laure, Haufroid Vincent

Abstract excerpt

AIM: To test the relevance of revisiting the genotype classification based on CYP3A5*3 solely by incorporating CYP3A4*22 information. METHODS: Discriminant analysis of principal component was performed to evaluate the relevance of either the CYP3A (CYP3A5 + CYP3A4 genotypes) or CYP3A5*3 classification variables. This analysis was based on a linear combination of noncompartmental pharmacokinetics parameters....

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Identifiers

PMID: 29095105
DOI: 10.2217/pgs-2017-0131

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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