Article

Pharmacogenomic Determinants of Post-Liver Transplant Diabetes Mellitus: A Systematic Review and In Silico Pharmacogenomic Analysis

2026-01-19

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Introduction</h4> Tacrolimus remains central to liver transplantation, yet its narrow therapeutic index and pharmacokinetic variability are associated with increased risk of post-transplant diabetes mellitus (PTDM). While polymorphisms in metabolizing enzymes modulate drug exposure and diabetogenic risk, these relationships have not been systematically integrated through targeted pharmacoge...

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Literature Corpus work: dfbf5546-4def-574e-b41d-db11604c1cd7
DOI: 10.64898/2026.01.17.26344329

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