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Article

Impact of CYP2D6 and ADRB1 polymorphisms on heart rate of post-PCI patients treated with metoprolol.

Pharmacogenomics - 1 Jan 2026

Gao Xiaofeng, Wang Huan, Chen Hui

Abstract excerpt

Aim: To explore the effect of CYP2D6*10 (100C > T) and ADRB1 1165 G > C polymorphisms on heart rate of post-PCI (percutaneous coronary intervention) patients treated with metoprolol succinate sustained-release tablets. Methods: A total of 756 inpatients with metoprolol succinate sustained-release tablets were selected and the genotypes of CYP2D6*10 and ADRB1 1165G > C were detected in 319 patients using gene chip...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Metoprolol

Share to Polymorphism, Genetic

Share to Polymorphism, Single Nucleotide

Share to Receptors, Adrenergic, beta-1

Source

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Identifiers

PMID: 29095089
DOI: 10.2217/pgs-2017-0203
PMCID: PMC13374743

Genes

ADRB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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