Article
Assessment of ADRB1 polymorphism in patients with acute coronary syndrome treated with ticagrelor and aspirin.
Personalized medicine - 1 Jan 2024
Zhang Xiang, Yuan Qi, Zhang Dawei
Abstract excerpt
Background: This study investigated the influence of ADRB1 gene rs1801253 polymorphism on the treatment response of ticagrelor and aspirin in patients with acute coronary syndrome (ACS). Methods: Genetic typing was detected by Sanger sequencing. Platelet inhibition was assessed using thromboelastography. Kaplan-Meier and Cox regression were applied for prognosis analysis. Results: Out of 200 participants,...
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