Article
Cg PDR 1 gain‐of‐function mutations lead to azole‐resistance and increased adhesion in clinical Candida glabrata strains
21 Feb 2018
Abstract excerpt
Summary Recently, Candida glabrata has emerged as a health‐threatening pathogen and the rising resistance to antifungal agent in C. glabrata often leads to clinical treatment failure. To investigate the evolution of drug resistance and adherence ability in four paired clinical isolates collected before and after antifungal treatment. Sequence analysis, gene disruption, drug‐susceptibility, adhesion tests and...
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