Article
The RS4939827 polymorphism in the SMAD7 GENE and its association with Mediterranean diet in colorectal carcinogenesis.
BMC medical genetics - 30 Oct 2017
Alonso-Molero Jéssica, González-Donquiles Carmen, Palazuelos Camilo, Fernández-Villa Tania, Ramos Elena, Pollán Marina, Aragonés Nuria, Llorca Javier, Henar Alonso M, Tardón Adonina, Amiano Pilar, Moleon José Juan Jiménez, Pérez Rosana Peiró, Capelo Rocío, Molina Antonio J, Acebo Inés Gómez, Guevara Marcela, Perez-Gomez Beatriz, Lope Virginia, Huerta José María, Castaño-Vinyals Gemma, Kogevinas Manolis, Moreno Victor, Martín Vicente
Abstract excerpt
BACKGROUND: The objective of our investigation is to study the relationship between the rs4939827 SNP in the SMAD7 gene, Mediterranean diet pattern and the risk of colorectal cancer. METHODS: We examined 1087 cases of colorectal cancer and 2409 population controls with available DNA samples from the MCC-Spain study, 2008-2012. Descriptive statistical analyses, and multivariate logistic mixed models were...
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