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Article

Association of SMAD7 genetic markers and haplotypes with colorectal cancer risk.

BMC medical genomics - 11 Jan 2022

Alidoust Maryam, Hamzehzadeh Leila, Khorshid Shamshiri Asma, Afzaljavan Fahimeh, Kerachian Mohammad Amin, Fanipakdel Azar, Aledavood Seyed Amir, Allahyari Abolghasem, Bari Alireza, Moosanen Mozaffari Hooman, Goshayeshi Ladan, Pasdar Alireza

Abstract excerpt

PURPOSE: Colorectal cancer (CRC) is one of the common cancers with a high mortality rate worldwide. In Iran, there has been a trend of increased incidence of colorectal cancer in the last three decades that necessitates the early diagnosis. Genetic factors have an influential role in its etiology along with the conventional risk factors such as age, diet, and lifestyle. Results from GWAS have shown significant...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genetic Predisposition to Disease

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 35016683
DOI: 10.1186/s12920-021-01150-3
PMCID: PMC8753827

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