Article
A common SMAD7 variant is associated with risk of colorectal cancer: evidence from a case-control study and a meta-analysis.
PloS one - 1 Jan 2012
Song Qibin, Zhu Beibei, Hu Weiguo, Cheng Liming, Gong Hongyun, Xu Bin, Zheng Xiawen, Zou Li, Zhong Rong, Duan Shengyu, Chen Wei, Rui Rui, Wu Jing, Miao Xiaoping
Abstract excerpt
BACKGROUND: A common genetic variant, rs4939827, located in SMAD7, was identified by two recent genome-wide association (GWA) studies to be strongly associated with the risk of colorectal cancer (CRC). However, the following replication studies yielded conflicting results. METHOD AND FINDINGS: We conducted a case-control study of 641 cases and 1037 controls in a Chinese population and then performed a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.