Association of several loci of SMAD7 with colorectal cancer: A meta-analysis based on case-control studies.

doi:10.1097/MD.0000000000032631

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Article

Association of several loci of SMAD7 with colorectal cancer: A meta-analysis based on case-control studies.

Medicine - 6 Jan 2023

Xiao Qiang, Chen Jian, Zhu Jia, Zeng Shukun, Cai Hu, Zhu Guomin

Abstract excerpt

BACKGROUND: Sma-and mad-related protein 7 (SMAD7) can affect tumor progression by closing transforming growth factor-beta intracellular signaling channels. Despite the extensive research on the correlation between SMAD7 polymorphisms and colorectal cancer (CRC), the conclusions of studies are still contradictory. We conducted a study focusing on the association of SMAD7 polymorphisms rs4939827, rs4464148, and...

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Identifiers

PMID: 36607878
DOI: 10.1097/MD.0000000000032631
PMCID: PMC9829263

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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