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Article

SMAD7 polymorphisms and colorectal cancer risk: a meta-analysis of case-control studies.

Oncotarget - 15 Nov 2016

Huang Yongsheng, Wu Wenting, Nie Meng, Li Chuang, Wang Lin

Abstract excerpt

Mothers against decapentaplegic homolog 7 (SMAD7) inhibits the transforming growth factor-β (TGF-β) signaling pathway, which regulates carcinogenesis and cancer progression. A number of studies have reported that SMAD7 polymorphisms (rs4464148, rs4939827, and rs12953717) are associated with colorectal cancer (CRC) risk, but the results from these studies remain conflicting. To determine a more precise estimation...

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Source

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Identifiers

PMID: 28070019
DOI: 10.18632/oncotarget.12285
PMCID: PMC5342761

Genes

SMAD7

Provenance

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