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Article

Intronic polymorphisms of the SMAD7 gene in association with colorectal cancer.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2015

Damavand Behzad, Derakhshani Shaghayegh, Saeedi Nastaran, Mohebbi Seyed Reza, Milanizadeh Saman, Azimzadeh Pedram, Aghdaie Hamid Asadzadeh, Zali Mohammad Reza

Abstract excerpt

Based on genome-wide association studies (GWAS) a linkage between several variants such as single nucleotide polymorphisms (SNPs) in intron 3 of SMAD7 (mothers against decapentaplegic homolog7) were, rs12953717, rs4464148 and rs4939827 has been noted for susceptibility to colorectal cancer (CRC). In this study we investigated the relationship of rs12953717 and rs4464148 with risk of CRC among 487 Iranian...

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Identifiers

PMID: 25640388
DOI: 10.7314/apjcp.2015.16.1.41

Genes

SMAD7

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