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Article

[Specificity and inheritance of rBE3 and rBE4 endonuclease-induced gene modifications in rice].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology - 25 Oct 2017

Ren Bin, Yan Fang, Kuang Yongjie, Li Na, Zhang Dawei, Lin Honghui, Zhou Huanbin

Abstract excerpt

To gain more insights into the rice base editor (rBE3 and rBE4), we evaluated the mutation efficiency, off-target and inheritance of OsSERK1(D428N) and pi-ta(S918F) genes modified with rBE endonucleases. We predicted and analyzed the putative off-target sites of the sgRNA designed for OsSERK1(D428N) and pi-ta(S918F) by PCR amplification and Sanger sequencing. Then we further characterized the inheritance and...

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Source

Identifiers

PMID: 29082724
DOI: 10.13345/j.cjb.170172

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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