Article
Biological function integrated prediction of severe radiographic progression in rheumatoid arthritis: a nested case control study.
Arthritis research & therapy - 25 Oct 2017
Joo Young Bin, Kim Yul, Park Youngho, Kim Kwangwoo, Ryu Jeong Ah, Lee Seunghun, Bang So-Young, Lee Hye-Soon, Yi Gwan-Su, Bae Sang-Cheol
Abstract excerpt
BACKGROUND: Radiographic progression is reported to be highly heritable in rheumatoid arthritis (RA). However, previous study using genetic loci showed an insufficient accuracy of prediction for radiographic progression. The aim of this study is to identify a biologically relevant prediction model of radiographic progression in patients with RA using a genome-wide association study (GWAS) combined with...
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