Article
Pathway-based association analysis of two genome-wide screening data identifies rheumatoid arthritis-related pathways.
Genes and immunity - 1 Oct 2014
Zhang M-M, Jiang Y-S, Lv H-C, Mu H-B, Li J, Shang Z-W, Zhang R-J
Abstract excerpt
The pathways can explain molecular mechanisms of complex diseases from the perspective of biology function. We carried out a genome-wide pathway-based association analysis to identify the risk pathways of rheumatoid arthritis (RA). First, we performed two genome-wide association studies using two RA data sets from GAW16 (Genetic Analysis Workshop 16) and the Wellcome Trust Case Control Consortium, and obtained...
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