Article
A systematic method for mapping multiple loci: an application to construct a genetic network for rheumatoid arthritis.
Gene - 31 Jan 2008
Li Chuanxing, Zhang Guangmei, Li Xia, Rao Shaoqi, Gong Binsheng, Jiang Wei, Hao Dapeng, Wu Peng, Wu Chao, Du Lei, Xiao Yun, Wang Yingying
Abstract excerpt
The advent of high-throughput single nucleotide polymorphisms (SNPs) omics technologies has brought tremendous genetic data. Systematic evaluation of the genome-wide SNPs is expected to provide breakthroughs in the understanding of complex diseases. In this study, we developed a new systematic method for mapping multiple loci and applied the proposed method to construct a genetic network for rheumatoid arthritis...
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