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Article

miR‐23b‐3p and miR‐125b‐5p downregulate apo(a) expression by targeting Ets1 in HepG2 cells

24 Oct 2017

Abstract excerpt

High concentrations of plasma lipoprotein(a) [Lp(a)] have been inferred to be an independent risk factor for cardiovascular and cerebrovascular diseases, such as coronary artery diseases, restenosis, and stroke. Apolipoprotein(a) [apo(a)] is one of the most important components of Lp(a) and contributes greatly to the increased concentration of plasma Lp(a). As a critical positive transacting factor of apo(a)...

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PMID: 29064597
DOI: 10.1002/cbin.10896

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