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Human Adipose-derived mesenchymal stem cells promote lymphocyte apoptosis and alleviate atherosclerosis via miR-125b-1-3p/BCL11B signal axis

1 Feb 2021

Abstract excerpt

BACKGROUND: Mesenchymal stem cells (MSCs) have shown great potential in the treatment of cardiovascular diseases, with fat being a more accessible source of MSCs. This study investigated the effect of human adipose-derived mesenchymal stem cells (hMSCs-Ad) exosomes on T lymphocytes and its role in atherosclerosis (AS). METHODS: The exosomes were preliminarily isolated hMSCs-Ad and co-cultured with human H9 T...

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PMID: 33725769
DOI: 10.21037/apm-21-49

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