Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MicroRNA-758 Regulates Cholesterol Efflux Through Posttranscriptional Repression of ATP-Binding Cassette Transporter A1

2 Sept 2011

Abstract excerpt

OBJECTIVE: The ATP-binding cassette transporter A1 (ABCA1) is a major regulator of macrophage cholesterol efflux and protects cells from excess intracellular cholesterol accumulation; however, the mechanism involved in posttranscriptional regulation of ABCA1 is poorly understood. We previously showed that microRNA-33 (miR-33) is 1 regulator. Here, we investigated the potential contribution of other microRNAs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Lipids, and Metabolism
Share to Cholesterol and Lipid Metabolism
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21885853
DOI: 10.1161/atvbaha.111.232066

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MicroRNA-758 Regulates Cholesterol Efflux Through Posttranscriptional Repression of ATP-Binding Cassette Transporter A1PMID 21885853Read ↗

Genome-wide identification of microRNAs regulating cholesterol and triglyceride homeostasis.Semantic proximity Read ↗

ABCA8 Regulates Cholesterol Efflux and High-Density Lipoprotein Cholesterol Levels.Semantic proximity Read ↗

The Regulation of Reverse Cholesterol Transport and Cellular Cholesterol Homeostasis by MicroRNAsSemantic proximity Read ↗

The Role of the ATP-Binding Cassette A1 (ABCA1) in Human Disease.Semantic proximity Read ↗

miR-758-5p regulates cholesterol uptake via targeting the CD36 3′UTRSemantic proximity Read ↗

Effects of miR-33 Deficiency on Metabolic and Cardiovascular Diseases: Implications for Therapeutic InterventionSemantic proximity Read ↗

MicroRNA-27a/b regulates cellular cholesterol efflux, influx and esterification/hydrolysis in THP-1 macrophagesSemantic proximity Read ↗

CTRP12 ameliorates atherosclerosis by promoting cholesterol efflux and inhibiting inflammatory response via the miR-155-5p/LXRα pathway.Semantic proximity Read ↗

The role of the ATP-Binding Cassette A1 (ABCA1) in neurological disorders: a mechanistic reviewSemantic proximity Read ↗

Efflux ABC transporters in drug disposition and their posttranscriptional gene regulation by microRNAsSemantic proximity Read ↗

Specific Disruption of Abca1 Targeting Largely Mimics the Effects of miR-33 Knockout on Macrophage Cholesterol Efflux and Atherosclerotic Plaque DevelopmentSemantic proximity Read ↗

Genetics of cholesterol efflux.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.