Article
DOSE AND DOSE-RATE DEPENDENCE OF DSB-TYPE MUTANTS INDUCED BY X-RAYS OR TRITIUM BETA-RAYS: AN APPROACH USING A HYPERSENSITIVE SYSTEM.
Radiation protection dosimetry - 9 Sept 2022
Nagashima Haruki, Hayashi Yuki, Tanimoto Saki, Sakamoto Yuki, Tauchi Hiroshi
Abstract excerpt
To evaluate biological effects triggered by low levels of radiation, we established a uniquely sensitive experimental system to detect somatic mutations. By using the system, we found that mutant frequencies induced by X-rays were statistically significant at doses over 0.15 Gy, and a linear dose relationship with the mutant frequency was observed at doses over 0.15 Gy. The mutation spectra analysis revealed that...
Topics
- Beta Particles
- DNA Breaks, Double-Stranded
- Dose-Response Relationship, Radiation
- Mutation
- Tritium
- X-Rays