Article
Host response to influenza infections in human blood: association of influenza severity with host genetics and transcriptomic response.
Frontiers in immunology - 1 Jan 2024
Schughart Klaus, Smith Amber M, Tsalik Ephraim L, Threlkeld Stephen C, Sellers Subhashini, Fischer William A, Schreiber Jens, Lücke Eva, Cornberg Markus, Debarry Jennifer, Woods Christopher W, McClain Micah T, Heise Mark
Abstract excerpt
Introduction: Influenza virus infections are a major global health problem. Influenza can result in mild/moderate disease or progress to more severe disease, leading to high morbidity and mortality. Severity is thought to be primarily driven by immunopathology, but predicting which individuals are at a higher risk of being hospitalized warrants investigation into host genetics and the molecular signatures of the...
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