Article
A pilot study of host genetic variants associated with influenza-associated deaths among children and young adults.
Emerging infectious diseases - 1 Dec 2011
Ferdinands Jill M, Denison Amy M, Dowling Nicole F, Jost Heather A, Gwinn Marta L, Liu Lindy, Zaki Sherif R, Shay David K
Abstract excerpt
We compared the prevalence of 8 polymorphisms in the tumor necrosis factor and mannose-binding lectin genes among 105 children and young adults with fatal influenza with US population estimates and determined in subanalyses whether these polymorphisms were associated with sudden death and bacterial co-infection among persons with fatal influenza. No differences were observed in genotype prevalence or minor allele...
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