Article
Clinical utility of plasma cell-free DNA in pancreatic neuroendocrine neoplasms.
Endocrine-related cancer - 1 Apr 2024
Cowzer Darren, Shah Ronak H, Chou Joanne F, Kundra Ritika, Punn Sippy, Fiedler Laura, DeMore April, Capanu Marinela, Berger Michael F, Reidy-Lagunes Diane, Raj Nitya
Abstract excerpt
In advanced pancreatic neuroendocrine neoplasms (PanNEN), there are little data detailing the frequency of genetic alterations identified in cell free DNA (cfDNA), plasma-tissue concordance of detected alterations, and clinical utility of cfDNA. Patients with metastatic PanNENs underwent cfDNA collection in routine practice. Next-generation sequencing (NGS) of cfDNA and matched tissue when available was...
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