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Liquid biopsies using pleural effusion-derived exosomal DNA in advanced lung adenocarcinoma

1 Aug 2019

Abstract excerpt

Background: Recently, plasma-derived exosomal DNA (exoDNA) has been successfully used in clinical genetic testing. However, the clinical utility of pleural effusion-derived exoDNA (PE-exoDNA) was still unknown. This study aimed to assess the feasibility of using PE-exoDNA for genetic testing in patients with advanced lung adenocarcinoma. Methods: Twenty PE-exoDNA samples and 18 pleural effusion-derived cell-free...

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PMID: 31555514
DOI: 10.21037/tlcr.2019.08.14

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