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Article

Functional diversity of miR-146a-5p and TRAF6 in normal and oral cancer cells.

International journal of oncology - 1 Nov 2017

Min Seung-Ki, Jung Sung Youn, Kang Hyun Ki, Park Sin-A, Lee Jong Ho, Kim Myung-Jin, Min Byung-Moo

Abstract excerpt

Numerous studies implicate miR-146a as pleiotropic regulator of carcinogenesis; however, its roles in carcinogenesis are not fully understood. A clue from expression analyses of miR-146a-5p in all 13 oral squamous cell carcinoma (OSCC) cell lines examined and in OSCC tissues, whole blood and whole saliva of OSCC patients in vivo revealed that miR‑146a-5p expression was highly upregulated. Particularly, we widened...

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Topics

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Share to Carcinoma, Squamous Cell
Share to Intracellular Signaling Peptides and Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to MicroRNAs

Share to Mouth Neoplasms

Share to RNA, Small Interfering

Share to Smad4 Protein

Share to TNF Receptor-Associated Factor 6

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Source

Identifiers

PMID: 29048658
DOI: 10.3892/ijo.2017.4124

Genes

TRAF6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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