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Article

Integrative approach detected association between genetic variants of microRNA binding sites of TLRs pathway genes and OSCC susceptibility in Chinese Han population.

PloS one - 1 Jan 2014

Wang Yun, Sun Chongkui, Li Taiwen, Xu Hao, Zhou Yu, Dan Hongxia, Jiang Lu, Zeng Xin, Li Longjiang, Li Jing, Liao Ga, Chen Qianming

Abstract excerpt

Oral squamous cell carcinoma (OSCC) is a leading malignancy worldwide; the overall 5-year survival rate is approximately 50%. A variety of proteins in Toll-like receptors (TLRs) pathway have been related with the risk of OSCC. However, the influence of genetic variations in TLRs pathway genes on OSCC susceptibility is unclear. Previous studies mainly focused on the coding region of genes, while the UTR region...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24999832
DOI: 10.1371/journal.pone.0101695
PMCID: PMC4085003

Genes

TRAF6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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