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Article

Dysregulation of miRNA-146a contributes to the development of lupus nephritis via targeting of TRAF6.

Personalized medicine - 1 Mar 2017

Wu Shupeng, Wang Jing, Li Fang

Abstract excerpt

AIM: The objective of this study was to identify the association between genotypes of miR-146a rs2910164 and expression of TRAF6 as well as the risk of lupus nephritis (LN). RESULTS: A total of 567 systemic lupus erythematosus patients both with and without LN were included in the study. The luciferase activity of cells that carried miR-146a mimics was much lower than control and the miR-146a mRNA expression with...

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Source

Identifiers

PMID: 29754557
DOI: 10.2217/pme-2016-0065

Genes

TRAF6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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