Article

Dental Follicle Mesenchymal Stem Cell-Derived Exosomes Mitigate Temporomandibular Joint Osteoarthritis in an In Vitro Model via the miR-146a-5p/Traf6/NF-κB Axis

2025-12-19

Abstract excerpt

<title>Abstract</title> <p>Interleukin-1β-induced inflammation in mandibular condylar chondrocytes (MCCs) plays a key role in temporomandibular joint (TMJ) osteoarthritis (OA), a common degenerative disease lacking effective treatments. Recently, mesenchymal stem cell-derived exosomes have been extensively studied for their therapeutic potential in treating various diseases. In this study, dental follicle stem ce...

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Literature Corpus work: a1e08563-4d01-5882-8da5-5c0c816c85ea
DOI: 10.21203/rs.3.rs-8341412/v1

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