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Article

A functional polymorphism in the pre-miR-146a gene is associated with the risk of nonsyndromic orofacial cleft.

Human mutation - 1 May 2018

Pan Yongchu, Li Dandan, Lou Shu, Zhang Chi, Du Yifei, Jiang Hongbing, Zhang Weibing, Ma Lan, Wang Lin

Abstract excerpt

microRNAs (miRNAs) are widely involved in craniofacial development, and genetic variants of miRNAs may be associated with the risk of nonsyndromic orofacial cleft (NSOC). Here, we systematically selected five single nucleotide polymorphisms (SNPs) of miRNAs and investigated the associations between these variants and NSOC susceptibility in a two-stage case-control study including 1,406 NSOC patients and 1,578...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29484780
DOI: 10.1002/humu.23415

Genes

TRAF6
CPO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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