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Article

Molecular basis for inner kinetochore configuration through RWD domain-peptide interactions.

The EMBO journal - 1 Dec 2017

Schmitzberger Florian, Richter Magdalena M, Gordiyenko Yuliya, Robinson Carol V, Dadlez Michał, Westermann Stefan

Abstract excerpt

Kinetochores are dynamic cellular structures that connect chromosomes to microtubules. They form from multi-protein assemblies that are evolutionarily conserved between yeasts and humans. One of these assemblies-COMA-consists of subunits Ame1CENP-U, Ctf19CENP-P, Mcm21CENP-O and Okp1CENP-Q A description of COMA molecular organization has so far been missing. We defined the subunit topology of COMA, bound with...

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Identifiers

PMID: 29046335
DOI: 10.15252/embj.201796636
PMCID: PMC5709738

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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