Article
GLRB variants regulate nearby gene expression in human brain tissues.
Scientific reports - 17 Oct 2017
Wu Qing-Jian, Yang Ming-Feng, Hao Pi-da, Yan Cheng-Jun, Du Chun-Jing, Li Han-Xia, Hou Ya-Jun, Sun Bao-Liang, Sun Shu-Yin
Abstract excerpt
A recent genome-wide association study (GWAS) identified four genetic variants rs78726293, rs191260602, rs17035816 and rs7688285 in GLRB gene to be associated with panic disorder (PD) risk. In fact, GWAS is an important first step to investigate the genetics of human complex diseases. In order to translate into opportunities for new diagnostics and therapies, we must identify the genes perturbed by these four...
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