Article
Association of RGS2 variants with panic disorder in a Japanese population.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jun 2011
Otowa Takeshi, Shimada Takafumi, Kawamura Yoshiya, Sugaya Nagisa, Yoshida Eiji, Inoue Ken, Yasuda Shin, Liu Xiaoxi, Minato Takanobu, Tochigi Mamoru, Umekage Tadashi, Kasai Kiyoto, Tanii Hisashi, Okazaki Yuji, Kaiya Hisanobu, Sasaki Tsukasa
Abstract excerpt
Panic disorder (PD) is a severe and chronic psychiatric disorder with significant genetic components underlying its etiology. The gene regulator of G protein signaling 2 (RGS2) has been reported to be associated with anxiety disorders. To confirm the association of RGS2 with PD, we investigated three single nucleotide polymorphisms (SNPs) of RGS2 (rs10801152, rs4606, and rs1819741) in 677 Japanese PD cases and...
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