Article
Epigenome-wide association study of DNA methylation in panic disorder.
Clinical epigenetics - 1 Jan 2017
Shimada-Sugimoto Mihoko, Otowa Takeshi, Miyagawa Taku, Umekage Tadashi, Kawamura Yoshiya, Bundo Miki, Iwamoto Kazuya, Tochigi Mamoru, Kasai Kiyoto, Kaiya Hisanobu, Tanii Hisashi, Okazaki Yuji, Tokunaga Katsushi, Sasaki Tsukasa
Abstract excerpt
BACKGROUND: Panic disorder (PD) is considered to be a multifactorial disorder emerging from interactions among multiple genetic and environmental factors. To date, although genetic studies reported several susceptibility genes with PD, few of them were replicated and the pathogenesis of PD remains to be clarified. Epigenetics is considered to play an important role in etiology of complex traits and diseases, and...
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