Article
Association analysis of Rgs7 variants with panic disorder.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Nov 2009
Hohoff Christa, Neumann Anna, Domschke Katharina, Jacob Christian, Maier Wolfgang, Fritze Jürgen, Bandelow Borwin, Krakowitzky Petra, Rothermundt Matthias, Arolt Volker, Deckert Jürgen
Abstract excerpt
Following our recent finding of Rgs2 playing a role in the development of human panic disorder (PD), we examine another positional and functional candidate from the functionally interwoven Rgs (regulator of G-protein signaling) family, Rgs7, in the pathogenesis of PD. A German PD sample (N = 224) was compared with matched controls (N = 224) for seven SNPs within and flanking the gene. The intronic SNP3...
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