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Genome stability of bovine in vivo-conceived cleavage-stage embryos is higher compared to in vitro-produced embryos

2 Sept 2017

Abstract excerpt

STUDY QUESTION: Is the rate and nature of chromosome instability (CIN) similar between bovine in vivo-derived and in vitro-cultured cleavage-stage embryos? SUMMARY ANSWER: There is a major difference regarding chromosome stability of in vivo-derived and in vitro-cultured embryos, as CIN is significantly lower in in vivo-derived cleavage-stage embryos compared to in vitro-cultured embryos. WHAT IS KNOWN ALREADY:...

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PMID: 29040498
DOI: 10.1093/humrep/dex286

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