Article

Single-blastomere next-generation sequencing confirms chromosomal abnormalities as the primary cause of impaired developmental potential in embryos with abnormal cleavage patterns

2026-08-18

Abstract excerpt

Abnormal cleavage impairs embryonic development, but the effects of different abnormal cleavage patterns and occurrence stages remain unclear. Previous chromosomal analyses at the blastocyst stage have failed to elucidate the underlying mechanism. This study investigated the effects of abnormal cleavage patterns and occurrence stages on embryonic developmental potential and clarified the association between abnorm...

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Literature Corpus work: 990761c4-e49d-5e58-b56d-73f72be617bd
DOI: 10.1186/s12958-026-01606-0

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